The main cause of heart failure is the heart's inability to circulate adequate blood to fulfill the body's metabolic needs. Myocardial infarction is the primary common cause of heart failure, despite the fact that a number of other reasons might contribute to such a condition. The considerable loss of cardiomyocytes after myocardial infarction is replaced by akinetic scar tissue instead of contracting cardiomyocytes. The short-term aim of maintaining ventricular integrity is met by such "wound healing," but the long-term effects include increasing fibrosis, stiffness, and dilatation of the ventricle. Therefore, two important areas to focus on in the failing heart are increasing mechanical performance and reducing remodeling.
Certain medical conditions can increase your risk for heart failure, including coronary artery disease (CAD) (the most common type of heart disease) and heart attacks, diabetes, high blood pressure, obesity, valvular heart disease, and other conditions related to heart disease.